Friday,DECember 10, 2021


Neuromodulation in the management of heart failure and its comorbidities: diabetes, sleep apnea and hypertension

08:00 - 09:40  |  Ballroom

Moderators: Howard Levin, Horst Sievert
Panelists: Marat Fudim, Jozef Bartunek, Philipp Lurz 

Translational concepts in the development of new treatment strategies  >> Kalyanam Shivkumar
Renal denervation for heart failure treatment: Renal denervation for HFpEF: trial design considerations - how can RDN learn from trials of inter-atrial shunt trials and SGLT-2 inhibitors 
>>  Philipp Lurz 
Renal denervation for heart failure treatment: Renal denervation for HFrEF: how to design trials given all the other treatments available - where would RDN fit in this crowded space? 
>>  Felix Mahfoud    
Treatment of central sleep apnea in heart failure patients: Remede 
>> Marat Fudim    
Stent-based barostimulation: Results of the first in man trial 
>> Horst Sievert 
An endovascular approach for treating HF patients using an implantable active Neuromodulation Implant 
>> Jozef Bartunek   
Metavention: Renal and hepatic artery denervation to treat metabolic syndrome 
>> Horst Sievert   

Pathogenesis and treatment of heart failure with preserved ejection fraction (HFpEF)

10:10 - 11:00  |  Ballroom

Moderator: Daniel Burkhoff, Gianluigi Savarese
Panelists: Piotr Ponikowski, Jozef Bartunek, Philipp Lurz
Q&A Facilitator: Gry Dahle

What are the underlying causes of HFpEF  >>  Rolf Wachter
The many faces of HFpEF – not just one disease 
>> Gianluigi Savarese
The failures, the learnings and the encouraging future - overview of potential therapies for HFpEF (medical therapy, clinical trial design, devices) 
>>  Piotr Ponikowski   
What is the causal role for Tricuspid Regurgitation in HFpEF? 
>> Yan Topilsky

The splanchnic bed is a novel target in patients with heart failure with preserved ejection fraction (HFpEF) s

11:00 - 12:15  |  Ballroom

Moderator: Howard Levin
Panelists: Marat Fudim, Piotr Ponikowski, Daniel Burkhoff

Overview of the physiology of the splanchnic bed in HFpEF and HFrEF  >> Marat Fudim   
Long-term follow-up on FIH endovascular therapy using the Satera Ablation System in HFpEF and HFrEF 
>> Sanjiv Shah   

Current status of the REBALANCE-HF US FDA randomized feasibility clinical trial in HFpEF  >> Sanjiv Shah   
Where does this therapy potentially fit into current landscape of treatments for HFpEF and HFrEF 
>> Piotr Ponikowski


12:30 - 14:00  |  Ballroom

Moderator: William Abraham, Stefan Anker
Panelists: Marat Fudim, David Kuraguntla, Jozef Bartunek
Q&A Facilitator: Martin Swaans

Telemedicine advancements during the COVID-19 pandemic: What's worked, what hasn't, and what's to come?  >> Marat Fudim  
Non-invasive assessment of lung fluid content 
>> Stefan Anker  
Implantable Hemodynamic Monitors: CardioMEMS  
>> Philip Adamson   
Implantable Hemodynamic Monitors: The first in heart microcomputer for the management of HF patients 
>> William Abraham    
Implantable Hemodynamic Monitors: Exercise stress testing in remote heart failure management  
>> Jozef Bartunek       
Non-invasive assessment of fluid status and arrthymogenic 
>> David Kuraguntla   

Non-invasive cardiac filling pressure compared with PCWP
 >> Yuhui Zhang

Durable mechanical circulatory support

14:00 - 15:10  |  Ballroom

Moderators: Navin Kapur, Daniel Burkhoff
Panelists: Gry Dahle, Petrus Jansen, Issam Moussa
Q&A Facilitator: Corstiaan den Uil    

CorWave LVAD - a biomimetic pump for physiologic pulsatility  >> Trevor Snyder  
HeartMate 3 
>>  Robert Kormos     
Carmat Aeson TAH  
>> Petrus Jansen

Evaheart  >>  Oliver Voigt  
Impella 5.5 
>> Bobbi Bogaev Chapman

Impella BRT  >> Sonya Bhavsar     

Acute mechanical circulatory support

15:40 - 17:10  | Ballroom

Moderators: Navin Kapur, Daniel Burkhoff
Panelists: Ralph D'Ambrosio, Rajan Patel, Jace Heuring, Corstian den Uil, Martin Swaans
Q&A Facilitator: Gry Dahle

Acute MCS state of the art  >> Jacob Moeller   
>> Amir Kaki   

ProtekDuo in COVID ARDS  >>  Amir Kaki 
Aortix EFS 
>> Jace Heuring   

SecondHeart  >> Leslie Miller

PreCardia EFS  >> Navin Kapur

PreCardia clinical trial  >> Michael Kiernan
New Impella RP 
>> Christoph Nix  
>> Corstiaan den Uil

Insights from the PULSE Trial & iVAC 2L in MCS facilitated high-risk PCI  >> Nicolas Van Mieghem

New and upcoming concepts and devices

17:10 - 18:00  |  Ballroom

Moderators: Navin Kapur, Daniel Burkhoff
Panelists: Ulrich Jorde, Yuval Binur, Sitaramesh Emani, Lee Goldberg
Q&A Faculitator: Horst Sievert

Synchronized diaphragmatic stimulation for the treatment of symptomatic heart failure  >> Lee Goldberg    
Importance of mitral valve plane movement in heart pumping - updated insights 
>> Ellen Ostenfeld 
Syntach - a novel minimally invasive cardiac support system 
>> Kristian Solem   

Doraya  >>  Ulrich Jorde
Targeting enhanced decongestion while aiming to preserve renal function – lymphatic-powered interstitial decongestion 
>> Sitaramesh Emani     
Percutaneous Pericardial Resection 
>> Barry A. Borlaug

Device Development Workshop

18:00 - 19:00  |  Ballroom

Moderator: Kathleen A. Marshall
Panelists: Yuval Binur, Florian Ludwig, Wolfgang Goetz


Cocktails, Covid and Recovery: How Innovators Adapt
Join a pre-cocktail fireside chat in which we talk about recovery and how things have adapted to a new environment and how some of what we have encountered has created opportunities for permanent change for the better, e.g. remote documentation, telehealth follow-up visits, digitalization of clinical data collection methods and links between actors. We will discuss real-world examples of inventive compliance and talk about how adapting to change in medicine is likely to generate better patient outcomes—all with the idea that innovation is about adaptation.



Saturday, DECember 11, 2021


E-poster presentation

07:00 - 08:00  |  Exhibition area

Electrotherapy for heart failure treatment

08:00 - 08:35  |  Ballroom

Moderators: Hendrik Bonnemeier, Horst Sievert
Panelists: Issam Moussa, Ralph Stephan von Bardeleben, Gry Dahle
Q&A Facilitator: Martin Bergmann

New trial results: More patients may benefit from CRT therapy!  >> Christian Butter   

CCM – Closing the gap: When OMT is not enough  >> Hendrik Bonnemeier 

Atrial fibrillation in heart failure  >> Christian Ukena

Interventions for LV Reconstruction and support

08:35 - 09:35  |  Ballroom

Moderators: Horst Sievert, Daniel Burkhoff
Panelists: Ralph Stephan von Bardeleben, Ulrich Jorde, Martin Swaans
Q&A Facilitator: Issam Moussa

Therapeutic opportunity & single center experience   >> Patrick Klein   
Predictors of Revivent LV restoration outcomes 
>> Rishi Puri   
The AccuCinch Ventricular Restoration System 
>> Ulrich Jorde    

V-sling: A left ventricular transcatheter repair device for HFrEF >> Horst Sievert
Transcatheter intramyocardial hydrogel injection (XDrop): FIM results 
>> Ling Tao   
Percutaneous radiofrequency ablation of HOCM 
>> Liwen Liu

Right heart failure

09:35 - 10:45  |  Ballroom

Moderators: Ralph Stephan von Bardeleben, Gry Dahle
Panelists: Markus Ferrari, Daniel Burkhoff, Martin Swaans
Q&A Facilitator: Kolja Sievert

Pathology and pathophysiology, clinical  relevance of RHF-does it help to treat TR?  >> Gry Dahle  
Evaluation of right ventricular function and its importance in RHF 
>> Martin Swaans   
Right heart failure in the guidelines 
>> Gry Dahle     
Mechanical assist in RHF using the PERKAT RV pulsatile right ventricular support device 
>> Markus Ferrari    
PHT in RHF, monitoring and treatment 
>> Tobias Ruf    
Tricuspid trial for RHF: Haemodynamic perspective 
>> Daniel Burkhoff

Valve interventions in patients with heart failure

11:15 - 12:50  |  Ballroom

Moderators: Nicolas Van Mieghem, Hueseyin Ince
Panelists: Issam Moussa, Philip Raake, Gry Dahle, Markus Ferrari, Martin Swaans, Daniel Kretzschmar
Q&A Facilitator: Tobias Ruf

Introduction  >> Hueseyin Ince     
Recent innovations for the management of patients with valvular heart disease – focus on heart failure 
>>  Eberhard Grube
2021  European guidelines on heart failure – focus on heart valves 
>> Marco Metra  
Echo criteria to identify TEER responders beyond COAPT 
>> Martin Swaans   
Volume outcome relation in percutaneous FMR treatment 
>> Alper Öner   
Role of the right sided heart in FMR 
>> Jeroen J Bax   
The impact of tricuspid regurgitation on patient outcomes 
>> David Messika-Zeitoun   
What do the guidelines say about tricuspid regurgitation? 
>> Marco Metra    
Status on transcatheter tricuspid valve interventions – when & how 
>> Philip Raake  
The current evidence and the vast clinical study & registry pipeline 
>> Jörg Hausleiter   
Case presentation: improving patient outcomes and QoL with a new device (PASCAL Ace) 
>> Leonhard Schneider   
Prevalence, prognosis, and management of exercise-induced severe MR in patients with heart failure 
>> Issam Moussa   
Closing remarks 
>> Nicolas Van Mieghem

Interatrial shunts

13:35 - 15:30  |  Ballroom

Moderators: William Abraham, Daniel Burkhoff, Horst Sievert
Panelists: Martin Bergmann, Dietmar Schranz, Ralph Stephan von Bardeleben
Q&A Facilitator: Martin Swaans

The physiological rationale for IASD as a treatment for heart failure  >> Daniel Burkhoff  
Lessons learned and being learned from the Corvia Reduce LAP-2 Study 
>> Sanjiv Shah   
IASD across the spectrum of EFs: The V-Wave experience 
>>  Michaela Hell 
Are different size shunts required? The AFR experience 
>>  Martin Bergmann  
Alternate means for creating a durable shunt without leaving a device behind:​ The Alleviant experience 
>> Lars Lund   
Alternate means of creating a durable shunt without leaving a device behind: The Noya experience 
>>   Chaim S. Lotan   
Alternate means of creating a durable shunt without leaving a device behind: The InterShunt experience 
>>   Horst Sievert 
Interatrial shunting for pulmonary hypertension 
>> William Abraham   
Clinical trial considerations for IASD pivotal studies 
>> Gregg W. Stone   
Interatrial shunt for end-stage amyloid heart disease (recorded case) 
>> Horst Sievert 

The future of device-based therapies and diagnostics for heart failure

16:00 - 16:30  |  Ballroom

Moderators: Howard Levin
Panelists: Issam Moussa, Martin Swaans, Yuval Binur
Q&A Facilitator: Marat Fudim

Cardiovascular innovations in Corona time  >> Yuval Binur    
We now have a drug therapy which is effective in HFpEF: Do we still need a device based therapy 
>> Deepak Bhatt

I am confused! Out of these 50+ treatment options – when to use what?

16:30 - 18:00   |  Ballroom

Moderators: Martin Bergmann, Horst Sievert
Panelists: Issam Mousa, Lee Goldberg, Daniel Burkhoff 
Q&A Facilitator:  Gry Dahle

Case 1  >>  Kolja Sievert
Case 2  
>>  Judith Steffan
Case 3  
>> Natalia Galeru